Synthesis, structural characterization and antibacterial studies of some biosensitive mixed ligand copper(II) complexes

A series of copper(II) complexes of mixed ligands with Schiff bases derived from 2-aminophenol/2-aminobenzoic acid with substituted benzaldehydes and 1,10-phenonthroline have been synthesized. Microanalytical, magnetic susceptibility, IR, UV-vis, CV, ESR and mass spectral techniques have been used to confirm the structure of these complexes. Their low electrical conductance values indicate that all the complexes are non-electrolytes. The monomeric nature of the complexes is evidenced from their magnetic susceptibility values. Electronic and EPR spectra of the complexes suggest that they have distorted octahedral geometry. The electrochemical behavior, the anodic and cathodic potential and the number of electron transfer have been calculated using cyclic voltammogram. The synthesized compounds have been tested against microorganisms such as Escherichia coli, Bacillus subtilis, Micrococcus luteus and Proteus vulgaris. A comparative study of the MIC values of the ligands and the complexes indicate that the complexes exhibit higher antibacterial activity than the free ligand and control.